1) Copy the files SpotRemover.vdf and SpotRemover.chm to the VirtualDub's plugins folder.
2) Start VirtualDub.
3) Select the Filters command in Video menu, and click Add button.
4) Select SpotRemover from the list of filters.
5) If you need, adjust the configurable parameters.
6) You can also use cropping to take out black areas at the edges, but keep in mind that SpotRemover will process only even frame dimensions.